A PROCESS FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE

摘要

The present invention is directed to an improved industrially viable, cost effective process for manufacturing 1 -benzyl-4-(5,6,-dimethoxyindanone-2-yl)methylpiperidine hydrochloride commonly known as donepezil hydrochloride in a substantially pure form with a purity level of greater than 99.9% and a novel crystalline form of 1- benzyl-4-(5,6,-dimethoxyindanone-2-yI)methylpiperidine in a substantially pure form.