| 摘要 |
Disclosed are 1-(arylmethyl)quinazoline-2,4(1H,3H)-diones thereof, represented by the Formula (I) wherein Ar, R1-R6 are defined herein. Compounds having Formula (I) are PARP inhibitors. Therefore, compounds of the invention may be used to treat clinical conditions that are responsive to the inhibition of PARP activity. |
| 申请人 |
IMPACT THERAPEUTICS, INC.;CAI, SUI XIONG;TIAN, YE EDWARD;DONG, HAIJUN;XU, QINGBING;WU, LIZHEN;LIU, LIJUN;JIANG, YANGZHEN;BAO, QINGLI;WANG, GUOXIANG;YIN, FENG;GU, CHENGYUN;HU, XIUHUA;WANG, XIAOZHU;KANG, SISHUN;CHEN, SHENGZHI |
发明人 |
CAI, SUI XIONG;TIAN, YE EDWARD;DONG, HAIJUN;XU, QINGBING;WU, LIZHEN;LIU, LIJUN;JIANG, YANGZHEN;BAO, QINGLI;WANG, GUOXIANG;YIN, FENG;GU, CHENGYUN;HU, XIUHUA;WANG, XIAOZHU;KANG, SISHUN;CHEN, SHENGZHI |
