发明名称 |
MicroRNA as a cancer progression predictor and its use for treating cancer |
摘要 |
The present invention is based on the findings that a novel function for miR142-3p in the regulation of Sox2, adenylyl cyclase 9 (AC9), and CD133 expressions, and consequently the overall stemness of recurrent GBM cells as well as CSCs, and that miR142-3p modulated tumor-initiating properties in recurrent GBM. The present invention consequently supports the development of novel miRNA-based strategies for brain tumor treatment. |
申请公布号 |
EP2505645(A1) |
申请公布日期 |
2012.10.03 |
申请号 |
EP20120160692 |
申请日期 |
2012.03.22 |
申请人 |
TAIPEI VETERANS GENERAL HOSPITAL |
发明人 |
CHIOU, SHIH-HWA;CHIOU, GUANG-YUH |
分类号 |
C12N15/113;A01K67/027;A61K31/7088;A61K31/713;A61P35/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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