TOPICAL IBUPROFEN FORMULATIONS

摘要

The present application relates to a topical formulation comprising ibuprofen, a hydroalcoholic based solvent system, a C1-4alcohol ester of citric acid, and a surfactant. The formulation shows physical stability over more than one month at ambient temperature and is colorless, essentially odorless, and has a pH value of about 6.5. The formulation of the application shows two to four times improved ibuprofen flux compared to a standard composition.