发明名称 Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of scleroderma
摘要 The invention relates to methods of treating, preventing, correcting and/or managing skin diseases or disorders characterized by overgrowths of the epidermis, keratoses, scleroderma, cutaneous vasculitis, acne or wrinkles are disclosed. Specific embodiments encompass the administration of an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof, alone or in combination with a second active agent. Specific second active ingredients are capable of affecting or inhibiting cell growth or proliferation, removing or improving acne scars, or reducing or correcting wrinkle lines. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also disclosed.
申请公布号 EP2505200(A1) 申请公布日期 2012.10.03
申请号 EP20120174490 申请日期 2005.03.18
申请人 CELGENE CORPORATION 发明人 ZELDIS, JEROME B.;HARIRI, ROBERT J.
分类号 A61K31/445;A61K31/19;A61K31/59;A61K36/28;A61K36/575;A61K38/21;A61K39/08;C07D401/00;C07D401/04 主分类号 A61K31/445
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