| 发明名称 |
siRNA compounds for inhibiting NRF2 |
| 摘要 |
The present invention provides chemically modified siRNA compounds that target the Nrf2 gene and pharmaceutical compositions comprising same useful for treating or preventing the incidence or severity of a cancerous disease, particularly various lung cancers. |
| 申请公布号 |
US8278287(B2) |
申请公布日期 |
2012.10.02 |
| 申请号 |
US20090988307 |
申请日期 |
2009.04.06 |
| 申请人 |
FEINSTEIN ELENA;METT IGOR;KALINSKI HAGAR;QUARK PHARMACEUTICALS INC. |
发明人 |
FEINSTEIN ELENA;METT IGOR;KALINSKI HAGAR |
| 分类号 |
A61K31/70;C07H21/02;C07H21/04 |
主分类号 |
A61K31/70 |
| 代理机构 |
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代理人 |
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