发明名称 |
N-pyrazole A2A receptor agonists |
摘要 |
The present disclosure provides a process for the preparation of 2-adenosine N-pyrazole compounds exemplified by the structure shown below that are potent and selective agonists for A2A adenosine receptor, compositions comprising these compounds, and methods for using these compounds to stimulate mammalian coronary vasodilation for imaging the heart. |
申请公布号 |
US8278435(B2) |
申请公布日期 |
2012.10.02 |
申请号 |
US20100968110 |
申请日期 |
2010.12.14 |
申请人 |
ZABLOCKI JEFF A.;ELZEIN ELFATIH O.;PALLE VENKATA;BELARDINELLI LUIZ;GILEAD SCIENCES, INC. |
发明人 |
ZABLOCKI JEFF A.;ELZEIN ELFATIH O.;PALLE VENKATA;BELARDINELLI LUIZ |
分类号 |
C07H19/00;C07H19/167;A61K31/7076;A61P7/00;A61P7/02;A61P9/00;A61P9/10;A61P29/00;A61P43/00;C07H19/16 |
主分类号 |
C07H19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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