| 摘要 |
A method within dynamic molecular imaging comprising dynamically estimating a first parameter (&bgr;(x)) and a second parameter (k(x)) of an activity function describing the bio distribution of an administered tracer, is disclosed. More specifically, the method comprises specifying a first target variance (&sgr;&bgr;,T(x)) and a second target variance (&sgr;&bgr;,T(x)) of the first parameter (&bgr;(x)) and the second parameter (k(x)) of the activity function, respectively; initiating an image acquisition; reconstructing the first parameter (&bgr;(x)) and the second parameter (k(x)); reconstructing a first associated variance (&sgr;&bgr;(x)) and a second associated variance (&sgr;k(x)) of the first parameter (&bgr;(x)) and the second parameter (k(x)), respectively; and repeating the image acquisition and the reconstructing until the first associated variance (&sgr;&bgr;(x)) and the second associated variance (&sgr;k(x)) are equal to or less than the first target variance (&sgr;&bgr;,T(x)) and the second target variance (&sgr;&bgr;,T(x)), respectively, &sgr;&bgr;(x)≦̸&sgr;&bgr;,T(x) and &sgr;k(x)≦̸&sgr;&bgr;,T(x). The method enables patient-specific adaptive protocols within molecular imaging. |
