发明名称 |
METHOD OF PRODUCING FULLERENE ADDUCTS |
摘要 |
FIELD: chemistry. ^ SUBSTANCE: disclosed is a method of producing fullerene adducts by mixing a dispersion of fullerene C60 with hydrophilic compounds, where the hydrophilic compound used is an amino acid or an amino sugar or polyhydroxylamine or a protein, which are first converted to a trimethylsilyl (TMS) derivative by mixing with a trimethyl silylating reagent (N,O-bis(trimethylsilyl)-acetamide in the medium of a polar aprotic solvent, after which the obtained solution of trimethylsilyl (TMS) derivative is mixed with a dispersion of fullerene in a polar aprotic solvent and the mixture is stirred at room temperature for 2-24 hours. ^ EFFECT: improved method. ^ 5 cl, 7 dwg, 7 ex |
申请公布号 |
RU2462474(C2) |
申请公布日期 |
2012.09.27 |
申请号 |
RU20100150483 |
申请日期 |
2010.12.09 |
申请人 |
FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "GOSUDARSTVENNYJ NAUCHNYJ TSENTR "INSTITUT IMMUNOLOGII" FEDERAL'NOGO MEDIKO-BIOLOGICHESKOGO AGENTSTVA |
发明人 |
ANDREEV SERGEJ MIKHAJLOVICH;BASHKATOVA ELENA NIKOLAEVNA;BASHKATOVA JULIJA NIKOLAEVNA;KHAITOV MUSA RAKHIMOVICH;PETRUKHINA ANNA OLEGOVNA |
分类号 |
A61K31/13;A61K31/197;A61K31/70;A61K38/38;C01B31/02;C07C215/06;C07C229/06;C07H5/06;C07K14/77 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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