| 发明名称 |
Method for producing soluble recombinant interferon protein without denaturing |
| 摘要 |
<p>The present invention relates to the field of recombinant protein production in bacterial hosts. It further relates to extraction of soluble, active recombinant protein from an insoluble fraction without the use of denaturation and without the need for a refolding step. In particular, the present invention relates to a production process for obtaining high levels a soluble recombinant Type 1 interferon protein from a bacterial host.</p> |
| 申请公布号 |
AU2011223627(A1) |
申请公布日期 |
2012.09.27 |
| 申请号 |
AU20110223627 |
申请日期 |
2011.03.02 |
| 申请人 |
PFENEX INC. |
发明人 |
ALLEN, JEFFREY;FENG, PING-HUA;PATKAR, ANANT;HANEY, KEITH L.;CHEW, LAWRENCE;SENGCHANTHALANGSY, LEI LEI PHOKHAM |
| 分类号 |
C07K14/555;C07K1/02;C12N15/20;C12N15/63;G01N33/68 |
主分类号 |
C07K14/555 |
| 代理机构 |
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