发明名称 Specific Antibodies To Amyloid Beta Peptide, Pharmaceutical Compositions And Methods Of Use Thereof
摘要 The invention relates to methods of treating a subject having Alzheimer's Disease, comprising the step of administering an antibody molecule which is targeted to &bgr; amyloid peptide or to fragment thereof. In another embodiment the invention relates to methods of treating a disease or a disorder, characterized by amyloid beta deposition. In another embodiment, the invention relates to an antibody molecule, which is free end-specific for the N-terminus or the C-terminus of an amyloid &bgr; peptide and to a pharmaceutical composition thereof. In another embodiment, the invention relates to an antibody molecule, which is targeted to the free C or N-terminus of a N- and/or C-terminus truncated amyloid &bgr; peptide fragment.
申请公布号 US2012244159(A1) 申请公布日期 2012.09.27
申请号 US201213445569 申请日期 2012.04.12
申请人 CHAIN DANIEL G.;INTELLECT NEUROSCIENCES INC. 发明人 CHAIN DANIEL G.
分类号 A61K39/395;A61K48/00;A61P25/28;C07K14/47;C07K16/18;C12P21/08 主分类号 A61K39/395
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