发明名称 |
SCREENING METHOD FOR SUBSTANCE CAPABLE OF PROMOTING RECOVERY OF SKIN BARRIER FUNCTION TECHNICAL FIELD |
摘要 |
The present invention provides a screening method for a substance capable of promoting recovery of skin barrier function, wherein the method comprises the steps of incubating caspase-14 and prosaposin in the presence of a candidate substance for the substance capable of promoting recovery of skin barrier function, and selecting the candidate substance as the substance capable of promoting recovery of skin barrier function when the degradation of prosaposin into saposin A is promoted significantly compared to a control substance.
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申请公布号 |
US2012244140(A1) |
申请公布日期 |
2012.09.27 |
申请号 |
US201013513528 |
申请日期 |
2010.12.03 |
申请人 |
HIBINO TOSHIHIKO;YAMAMOTO MAMI;SHISEIDO COMPANY, LTD. |
发明人 |
HIBINO TOSHIHIKO;YAMAMOTO MAMI |
分类号 |
A61K38/48;A61P17/02;C12Q1/37;G01N33/573 |
主分类号 |
A61K38/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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