发明名称 ARYLOXYANILIDE IMAGING AGENTS
摘要 The present invention provides a novel radiolabeled aryloxyalinine derivative suitable for in vivo imaging. In comparison to known aryloxyalinine derivative in vivo imaging agents, the in vivo imaging agent of the present invention has better properties for in vivo imaging. The in vivo imaging agent of the present invention demonstrates good selective binding to the peripheral benzodiazepine receptor (PBR), in combination with good brain uptake and in vivo kinetics following administration to a subject.
申请公布号 US2012244073(A1) 申请公布日期 2012.09.27
申请号 US201013510041 申请日期 2010.12.16
申请人 WADSWORTH HARRY JOHN;O' SHEA DENNIS 发明人 WADSWORTH HARRY JOHN;O' SHEA DENNIS
分类号 A61K51/04;B01L3/00;C07D307/79;C07D317/60;C07D319/18 主分类号 A61K51/04
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