METHODS OF GROWING TUMOR INFILTRATING LYMPHOCYTES IN GAS-PERMEABLE CONTAINERS

摘要

An embodiment of the invention provides TIL prepared by obtaining a tumor tissue sample obtaining tumor infiltrating lymphocytes (TIL) from the tumor tissue sample and expanding the number of TIL in a gas permeable container containing cell medium therein using irradiated allogeneic feeder cells and/or irradiated autologous feeder cells; for use in promoting the regression of cancer in a mammal. Methods of preparing an expanded number of TIL are also provided.