发明名称 FOXM1 PEPTIDE AND MEDICINAL AGENT COMPRISING THE SAME
摘要 <p>315 An objective of the present invention is to provide a means for enabling cancerimmunotherapy that targets approximately 30% of various cancer patients that highly express forkhead box M1 (FOXM1) among the Japanese, by identifying FOXMl-derived peptides that can activate cancer cell-damaging human killer T cells by binding to HLA-A2. The present invention provides a peptide of (A) or (B) below:10 (A) a peptide including the amino acid sequence of any one of SEQ ID NOs: 1 to 3;(B) a peptide which includes the amino acid sequence of any one of SEQ ID NOs: 1 to 3, wherein one, two, or several amino acid(s) are substituted, deleted, inserted, and/or added, and wherein the peptide shows cytotoxic (killer) T cell-inducing activity.15 (No Suitable Figure)</p>
申请公布号 SG183717(A1) 申请公布日期 2012.09.27
申请号 SG20120059549 申请日期 2008.08.12
申请人 ONCOTHERAPY SCIENCE, INC. 发明人 NISHIMURA, YASUHARU;YOKOMINE, KAZUNORI;TSUNODA, TAKUYA;NAKAMURA, YUSUKE
分类号 C12N5/0783 主分类号 C12N5/0783
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