发明名称 PYRIDIN-2-YL-AMINO-I,2,4-THIADIAZOLE DERIVATIVES AS GLUCOKINASE ACTIVATORS FOR THE TREATMENT OF DIABETES MELLITUS
摘要 Provided are compounds of Formula I wherein R 2 , R 3 , R 13 , L and D 2 are as defined in the specification, which are useful in the treatment and/or prevention of diseases or disorders mediated by deficient levels of glucokinase activity or which can be treated by activating glucokinase including, but not limited to, diabetes mellitus, impaired glucose tolerance, IFG (impaired fasting glucose) and IFG (impaired fasting glycemia), as well as other diseases and disorders such as those discussed herein.
申请公布号 ZA201102350(B) 申请公布日期 2012.09.26
申请号 ZA20110002350 申请日期 2011.03.29
申请人 ARRAY BIOPHARMA INC 发明人 AICHER THOMAS DANIEL;BOYD STEVEN ARMEN;CHICARELLI MARK JOSEPH;CONDROSKI KEVIN RONALD;FELL JAY BRADFORD;FISCHER JOHN P;GUNAWARDANA INDRANI W;HINKLIN RONALD JAY;SINGH AJAY;TURNER TIMOTHY M;WALLACE ELI M
分类号 A61K;A61P;C07D 主分类号 A61K
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