发明名称 |
METHOD FOR PRODUCING T CELL RECEPTOR-LIKE MONOCLONAL ANTIBODIES AND USES THEREOF |
摘要 |
<p>Methods are provided for producing T cell receptor (TCR) like antibodies that recognize peptides displayed in the context of HLA molecules. Antibodies produced by methods provided herein have the specificity of a TCR and can be used as therapeutic, diagnostic and research reagents. Also provided are TCR-like antibodies which recognize Epstein-Barr virus (EBV) peptides displayed in the context of HLA molecules and are useful for the detection and treatment of EBV and EBV-linked diseases.</p> |
申请公布号 |
EP2501722(A1) |
申请公布日期 |
2012.09.26 |
申请号 |
EP20100831884 |
申请日期 |
2010.11.18 |
申请人 |
NATIONAL UNIVERSITY OF SINGAPORE;DSO NATIONAL LABORATORIES |
发明人 |
MACARY, PAUL ANTHONY;CHAN, SOH, HA;HANSON, BRENDON, JOHN |
分类号 |
C07K16/08;A61K39/00;A61K39/395;C07K7/06;C07K16/00;C07K16/28;C07K16/30;C12P21/00;C12P21/08;G01N33/53 |
主分类号 |
C07K16/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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