发明名称 |
Predictors of patient response to treatment with EGF receptor inhibitors |
摘要 |
The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness. |
申请公布号 |
US8273534(B2) |
申请公布日期 |
2012.09.25 |
申请号 |
US20090465503 |
申请日期 |
2009.05.13 |
申请人 |
BAKER JOFFRE B.;WATSON DREW;MADDALA TARA;SHAK STEVEN;MAURO DAVID J.;FORD SHIRIN K.;GENOMIC HEALTH, INC.;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
BAKER JOFFRE B.;WATSON DREW;MADDALA TARA;SHAK STEVEN;MAURO DAVID J.;FORD SHIRIN K. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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