4-[CYCLOALKYLOXY (HETERO) ARYLAMINO] THIENO [2,3-D] PYRIMIDINES HAVING MNKL/MNK2 INHIBITING ACTIVITY FOR PHARMACEUTICAL COMPOSITIONS

摘要

The present invention relates to novel thienopyrimidine compounds of general formula pharmaceutical compositions comprising these compounds and their therapeutic use for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof.