发明名称 ANGIOTENSIN II RECEPTOR ANTAGONISTS
摘要 A compound having the structure wherein R is, for example, Y is selected from the group consisting of 1) R5, 2) —C(R1R2) (C(R3R4))0-1Y1R5, and 3) —C(R1R2)—O—Y1R5; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1-4 alkyl; R5 is; Y1 is selected from the group consisting of C(O)—O— and P(O)(OR6)—O—; and R6 is hydrogen or CH3, or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension.
申请公布号 US2012238608(A1) 申请公布日期 2012.09.20
申请号 US201213483213 申请日期 2012.05.30
申请人 ALI AMJAD;LO MICHAEL MAN-CHU;SEBHAT IYASSU K.;FRANKLIN CHRIS;ALMIRANTE NICOLETTA;STEFANINI SILVIA;BIONDI STEFANO;ONGINI ENNIO;MERCK SHARP & DOHME 发明人 ALI AMJAD;LO MICHAEL MAN-CHU;SEBHAT IYASSU K.;FRANKLIN CHRIS;ALMIRANTE NICOLETTA;STEFANINI SILVIA;BIONDI STEFANO;ONGINI ENNIO
分类号 A61K31/4178;A61P9/12;C07D493/04 主分类号 A61K31/4178
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