发明名称 |
SULFONAMIDE COMPOUNDS HAVING TRPM8 ANTAGONISTIC ACTIVITY |
摘要 |
<p>Sulfonamide compounds having TRPM8 antagonistic activity are provided. A sulfonamide compound of formula (I) or a pharmaceutically acceptable salt thereof, or a prodrug thereof: (I) wherein Ring A is bicyclic aromatic heterocycle comprised of (a) pyridine is condensed with benzene; or (b) pyridine is condensed with monocyclic aromatic heterocycle, and Ring A binds to a sulfonylamino moiety on a carbon atom adjacent to a nitrogen atom of the pyridine ring constituting Ring A, Ring B is (a) monocyclic or bicyclic aromatic hydrocarbon; (b) monocyclic or bicyclic alicyclic hydrocarbon; (c) monocyclic or bicyclic aromatic heterocycle; or (d) monocyclic or bicyclic non-aromatic heterocycle, Ring C is (a) benzene; or (b) monocyclic aromatic heterocycle, and other symbols are the same as defined in the specification.</p> |
申请公布号 |
CA2826678(A1) |
申请公布日期 |
2012.09.20 |
申请号 |
CA20122826678 |
申请日期 |
2012.03.15 |
申请人 |
MITSUBISHI TANABE PHARMA CORPORATION |
发明人 |
TSUZUKI, YASUYUKI;SAWAMOTO, DAISUKE;SAKAMOTO, TOSHIAKI;KATO, TAKU;NIWA, YASUKI;AWAI, NOBUMASA |
分类号 |
C07D217/22;A61K31/47;A61K31/4725;C07D401/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D471/04 |
主分类号 |
C07D217/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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