发明名称 BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION
摘要 The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
申请公布号 WO2012125598(A1) 申请公布日期 2012.09.20
申请号 WO2012US28843 申请日期 2012.03.13
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH;ABEYWARDANE, ASITHA;BURKE, MICHAEL J.;KIRRANE, THOMAS MARTIN, JR.;NETHERTON, MATTHEW RUSSELL;PADYANA, ANIL KUMAR;SMITH KEENAN, LANA LOUISE;TAKAHASHI, HIDENORI;TURNER, MICHAEL ROBERT;ZHANG, QIANG;ZHANG, QING 发明人 ABEYWARDANE, ASITHA;BURKE, MICHAEL J.;KIRRANE, THOMAS MARTIN, JR.;NETHERTON, MATTHEW RUSSELL;PADYANA, ANIL KUMAR;SMITH KEENAN, LANA LOUISE;TAKAHASHI, HIDENORI;TURNER, MICHAEL ROBERT;ZHANG, QIANG;ZHANG, QING
分类号 C07D319/20;A61K31/357;A61P19/00;A61P29/00;C07D405/10;C07D405/12;C07D405/14;C07D487/10 主分类号 C07D319/20
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