发明名称 |
CHITOSAN PATCH SCAFFOLD RELEASING GROWTH FACTORS AND ITS FABRICATING METHOD FOR REPAIRING CHRONIC TYMPANIC MEMBRANE PERFORATIONS |
摘要 |
PURPOSE: A chitosan patch scaffold releasing growth factors, and a producing method thereof are provided to treat the chronic tympanic membrane perforation. CONSTITUTION: A producing method of a chitosan patch scaffold releasing growth factors comprises the following steps: producing a solution by controlling the concentration of chitosan and glycerol; adding the growth factors into the solution; adjusting the amount of the solution to form a patch shape; and drying the solution to obtain the patch scaffold. The concentration of the chitosan is 2-5%, and the concentration of the glycerol is 1-5%. The growth factors are selected from an epidermal growth factor, a fiber blast growth factor, insulin-like growth factor binding protein, or their combination. [Reference numerals] (AA) Treating process of chronic generation of eardrum holes EGF eluting chitosan patch VS a control group
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申请公布号 |
KR20120103773(A) |
申请公布日期 |
2012.09.20 |
申请号 |
KR20110020472 |
申请日期 |
2011.03.08 |
申请人 |
SNU R&DB FOUNDATION;AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION |
发明人 |
CHUNG, JONG HOON;CHOUNG, YUN HOON;SEON, WOO HOON |
分类号 |
A61F2/18;A61F11/00;A61L27/40;A61L27/54 |
主分类号 |
A61F2/18 |
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