| 发明名称 |
METHODS OF PREPARATION OF CONJUGATES |
| 摘要 |
The present invention is directed to methods of preparing a conjugate of a cell-binding agent and a drug (such as a cytotoxic compound). The methods comprise the use of an imine reactive compound to enable efficient conjugations of cytotoxic compounds with cell binding agents.
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| 申请公布号 |
US2012238731(A1) |
申请公布日期 |
2012.09.20 |
| 申请号 |
US201213397205 |
申请日期 |
2012.02.15 |
| 申请人 |
FISHKIN NATHAN;MILLER MICHAEL;LI WEI;SINGH RAJEEVA;IMMUNOGEN, INC. |
发明人 |
FISHKIN NATHAN;MILLER MICHAEL;LI WEI;SINGH RAJEEVA |
| 分类号 |
C07K16/46 |
主分类号 |
C07K16/46 |
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