发明名称 |
Involvement of androgen/androgen receptor pathway in Fabry disease |
摘要 |
Novel therapies for the treatment of Fabry disease by using androgen/androgen receptor (AR) pathway-related molecules as biomarkers and use of approaches targeting androgen/ AR pathway are presented herein. The involvement of aberrant androgen/AR pathway in Fabry disease has never been previously described. The present invention describes, (i) use of approaches that target androgen/AR pathway as therapeutic treatments for Fabry disease and (2) use of the levels of androgen/AR pathway-related molecules in body fluids or tissues as biomarkers for evaluation of disease progression and efficacy of treatments in Fabry patients. |
申请公布号 |
AU2011223706(A1) |
申请公布日期 |
2012.09.20 |
申请号 |
AU20110223706 |
申请日期 |
2011.03.01 |
申请人 |
BAYLOR RESEARCH INSTITUTE |
发明人 |
SHEN, JINSONG;SCHIFFMANN, RAPHAEL;MENG, XINGLI |
分类号 |
C12Q1/00;A61K38/00;A61P3/00;A61P5/26;G01N33/483;G01N33/487 |
主分类号 |
C12Q1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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