发明名称 Monoconjugated Chitosans as Delivery Agents for Small Interfering Nucleic Acids
摘要 Conjugates are provided, an exemplary conjugating having a single water-soluble, non-peptidic polymer, such as a poly(ethylene oxide), attached to a chitosan. Complexes of small interfering nucleic acids formed with such conjugates as well as small interfering nucleic acids attached to such conjugates are also provided. Related methods, intermediates, and compositions are also provided.
申请公布号 US2012238735(A1) 申请公布日期 2012.09.20
申请号 US201013496170 申请日期 2010.09.16
申请人 MCMANUS SAMUEL P.;KOZLOWSKI ANTONI;YOUSO PATRICK D.;NEKTAR THERAPEUTICS 发明人 MCMANUS SAMUEL P.;KOZLOWSKI ANTONI;YOUSO PATRICK D.
分类号 C07H21/02;C08B37/08 主分类号 C07H21/02
代理机构 代理人
主权项
地址