INJECTABLE DELIVERY SYSTEM FOR HEPARAN SULFATE BINDING GROWTH FACTORS
摘要
A method for enhancing chondrogenesis in a subject in need thereof comprises administering to the subject an effective amount of a pharmaceutical composition comprising a growth factor bound to hyaluronic acid (HA)-based hydrogel particles (HGPs). The hyaluronic acid (HA)-based hydrogel particles (HGPs) are conjugated with a heparan sulfate proteoglycan (HSPG). Related medicaments and methods for preparing the medicaments are provided.
申请公布号
WO2012125914(A1)
申请公布日期
2012.09.20
申请号
WO2012US29411
申请日期
2012.03.16
申请人
UNIVERSITY OF DELAWARE;SAFRAN, CATHERINE B.;FARACH-CARSON, MARY C.;JIA, XINQIAO;SRINIVASAN, PADMA P.;JHA, AMIT
发明人
SAFRAN, CATHERINE B.;FARACH-CARSON, MARY C.;JIA, XINQIAO;SRINIVASAN, PADMA P.;JHA, AMIT