METHOD FOR IMPROVING MEASUREMENT ACCURACY OF MICROORGANISM HEAT PRODUCTION IN FERMENTATION VESSEL

摘要

FIELD: medicine. ^ SUBSTANCE: method involves measuring heat production by variation of heat rate consumed by maintenance of the isothermal mode of a fermentation vessel with intermitted fluid and gas flows through the fermentation vessel with adjusted heat power consumption by mixing the culture fluid. It is combined with eliminating heat power consumption by heat production in the fermentation vessel of the culture fluid mass due to maintaining its initial value at the pre-set accuracy in the environment of the conducted continuous and periodic cultivation processes by equation of energy gain, consumed for each heating cycle of the fermentation vessel, the energy gain value derived by calibration heating of the fermentation vessel filled with the initial culture fluid mass with the heat production value and the maintenance of the culture fluid mass during the microorganism cultivation process are spread out over a period of time. ^ EFFECT: increased measurement accuracy of continuous and periodic microorganism heat production in the fermentation vessel. ^ 2 cl, 3 dwg