发明名称 |
ANTIBODY, PHARMACEUTICAL COMPOSITION USED FOR TREATMENT OF BREAST CANCER, TUMOR TEST METHOD, AND REAGENT FOR TESTING TUMOR |
摘要 |
<p>Provided are an antibody and a pharmaceutical composition, both of which are effective for the treatment of breast cancer, particularly a triple-negative case of breast cancer. An antibody capable of binding specifically to a extracellular domain of EphA10 is allowed to act. An example of the extracellular domain is a fibronectin domain. The EphA10 positive ratio is about 67% in a triple-negative case. In a biological sample separated from a living body, EphA10 can be detected as a tumor marker for stomach cancer, prostate cancer or colorectal cancer.</p> |
申请公布号 |
WO2012124334(A1) |
申请公布日期 |
2012.09.20 |
申请号 |
WO2012JP01802 |
申请日期 |
2012.03.14 |
申请人 |
NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION;TSUNODA, SHINICHI;NAGANO, KAZUYA;TSUTSUMI, YASUO |
发明人 |
TSUNODA, SHINICHI;NAGANO, KAZUYA;TSUTSUMI, YASUO |
分类号 |
C07K16/28;A61K39/395;A61P35/00;C12N15/09;C12P21/08;C12Q1/68;G01N33/574;G01N33/68 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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