发明名称 ANTIBODY, PHARMACEUTICAL COMPOSITION USED FOR TREATMENT OF BREAST CANCER, TUMOR TEST METHOD, AND REAGENT FOR TESTING TUMOR
摘要 <p>Provided are an antibody and a pharmaceutical composition, both of which are effective for the treatment of breast cancer, particularly a triple-negative case of breast cancer. An antibody capable of binding specifically to a extracellular domain of EphA10 is allowed to act. An example of the extracellular domain is a fibronectin domain. The EphA10 positive ratio is about 67% in a triple-negative case. In a biological sample separated from a living body, EphA10 can be detected as a tumor marker for stomach cancer, prostate cancer or colorectal cancer.</p>
申请公布号 WO2012124334(A1) 申请公布日期 2012.09.20
申请号 WO2012JP01802 申请日期 2012.03.14
申请人 NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION;TSUNODA, SHINICHI;NAGANO, KAZUYA;TSUTSUMI, YASUO 发明人 TSUNODA, SHINICHI;NAGANO, KAZUYA;TSUTSUMI, YASUO
分类号 C07K16/28;A61K39/395;A61P35/00;C12N15/09;C12P21/08;C12Q1/68;G01N33/574;G01N33/68 主分类号 C07K16/28
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