发明名称 |
Amine compound and use thereof for medical purposes |
摘要 |
Disclosed is a novel amine compound represented by the general formula (I) below, a pharmaceutically acceptable acid addition salt of the compound, or a hydrate or solvate of the compound or the salt, which is excellent in an immunosuppressing effect, a rejection response-suppressing effect and the like and is reduced in adverse side effects such as bradycardia. Also disclosed is a pharmaceutical composition comprising the compound and a pharmaceutically acceptable carrier. (I) wherein R represents a hydrogen atom or P(=O)(OH); X represents an oxygen or sulfur atom; Y represents CHCH or CH=CH; R represents an alkyl having 1-4 carbon atoms which is substituted by a halogen atom or a cyano; R represents an alky having 1-4 carbon atoms which may be substituted by a hydroxyl group or a halogen atom; R and R independently represent a hydrogen atom or an alkyl having 1-4 carbon atoms; and n represents 5-8. |
申请公布号 |
AU2006325931(A8) |
申请公布日期 |
2012.09.20 |
申请号 |
AU20060325931 |
申请日期 |
2006.12.15 |
申请人 |
MITSUBISHI TANABE PHARMA CORPORATION |
发明人 |
MARUKAWA, KAORU;SUGAHARA, KUNIO;KIUCHI, MASATOSHI;KOBAYASHI, NOBUTAKA |
分类号 |
C07C217/64;A61K31/137;A61K31/165;A61K31/222;A61K31/277;A61K31/325;A61K31/351;A61K31/357;A61K31/661;A61K31/675;A61K31/695;A61P3/10;A61P11/06;A61P13/12;A61P17/00;A61P17/06;A61P19/00;A61P19/02;A61P25/00;A61P27/16;A61P29/00;A61P37/02;A61P37/06;C07C255/59;C07C323/32;C07C323/43;C07F9/09 |
主分类号 |
C07C217/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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