摘要 |
<p>The present invention is directed to quinazolinyl and pyridoquinazolinyl compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.</p> |
申请人 |
MERCK SHARP & DOHME CORP.;GREEN, AHREN;LI, YIWEI;STACHEL, SHAWN |
发明人 |
GREEN, AHREN;LI, YIWEI;STACHEL, SHAWN |