STRAIN ASPERGILLUS OCHRACEUS - HUMAN BLOOD PLASMA PROTEIN C ACTIVATOR PROTEINASE PRODUCER

摘要

FIELD: medicine. ^ SUBSTANCE: Aspergillus ochraceus strain is recovered from soil sampled in Krasnodar Territory and deposited in Russian National Collection of Microorganisms, No. F-4104D. The strain produces proteinase being a human blood plasma protein C activator into a culture fluid while grown on a medium containing carbohydrate and protein compounds, and mineral salts. Anticoagulant activity of the strain to prolong activated partial thromboplastin time by 2 cultivation days makes 960%. Proteinase activity of the strain Aspergillus ochraceus in the culture fluid determined with the use of chromogenic peptide substrate pGlu-Pro-Arg-pNA makes 77.5 units/ml. ^ EFFECT: higher proteinase activity of said strain. ^ 1 tbl, 2 ex