发明名称 |
PROCESS FOR THE PREPARATION OF (2R,3S)-2-(HYDROXYMETHYL)-5-METHOXYTETRAHYDROFURAN-3-OL AND ACETYLATED DERIVATIVES THEREOF, FREE OF PYRANOSE COMPOUNDS |
摘要 |
A method of preparing a ribofuranose derivative essentially free of pyranose compounds includes a step of contacting a solution of MDR containing MDRP as an impurity in a solvent including methanol and/or tetrahydrofuran with at least one alkali metal periodate under conditions sufficient to oxidize at least a portion of the MDRP. MDR containing at most 5 wt % of MDRP based on the total weight of MDR and MDRP may be produced. |
申请公布号 |
US2012238734(A1) |
申请公布日期 |
2012.09.20 |
申请号 |
US201113303710 |
申请日期 |
2011.11.23 |
申请人 |
FU XING;ZUMBRUNN ALBRECHT;JOHNSON MATTHEY PUBLIC LIMITED COMPANY |
发明人 |
FU XING;ZUMBRUNN ALBRECHT |
分类号 |
C07H1/06;C07H1/00;C07H15/04 |
主分类号 |
C07H1/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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