<p>Surgical staple cartridge and channel assemblies for attachment to a surgical cutting and stapling instrument. It is disclosed an integrated surgical fastener cartridge assembly comprising: an elongated channel configured for removable attachment to a distal frame portion of a surgical instrument, said elongated channel having an attachment portion comprising: - a wedge-shaped portion configured for wedging engagement with the distal frame portion; and -a locking member for releasably retaining said wedge-shaped portion in wedging engagement with the distal frame portion and wherein said integrated surgical fastener cartridge further comprises a cartridge body supported in said elongated channel and operably supporting a plurality of tissue fasteners therein.</p>
