| 发明名称 |
METHOD FOR PRODUCING PARACETAMOL |
| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: what is offered is a method for producing paracetamol consisting in n-nitrosophenol recovery in ethyl acetate in the presence of the Pd/C-containing catalyst at hydrogen pressure 2.0-4.0 atm and temperature 20-50C that is followed by acylation of formed n-aminophenol and end product recovery. ^ EFFECT: simplified technology and higher end product yield. ^ 1 cl, 4 ex |
| 申请公布号 |
RU2461543(C1) |
申请公布日期 |
2012.09.20 |
| 申请号 |
RU20110123808 |
申请日期 |
2011.06.10 |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE AVTONOMNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "URAL'SKIJ FEDERAL'NYJ UNIVERSITET IMENI PERVOGO PREZIDENTA ROSSII B.N. EL'TSINA" |
发明人 |
AZEV JURIJ ALEKSEEVICH;CHARUSHNIKOV KIRILL ALEKSANDROVICH;MOKRUSHIN VLADIMIR STEPANOVICH;GIBOR ALEKSEJ MIKHAJLOVICH |
| 分类号 |
A61K31/167;A61P29/00;C07C231/10;C07C233/25 |
主分类号 |
A61K31/167 |
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