发明名称 |
Nucleic acid construct systems capable of diagnosing or treating a cell state |
摘要 |
<p>The present invention relates to a nucleic acid construct system comprising (i) first nucleic acid construct comprising a first polynucleotide, said first polynucleotide comprising a first nucleic acid sequence encoding a first expression product, said first nucleic acid sequence being operably linked to a first inducible mammalian transcriptional regulatory sequence; and (ii) second nucleic acid construct comprising a second polynucleotide, said second polynucleotide comprising a second nucleic acid sequence encoding a second expression product, said second nucleic acid sequence being operably linked to a second inducible mammalian transcriptional regulatory sequence, wherein: (a) said first inducible mammalian transcriptional regulatory sequence and said second inducible mammalian transcriptional regulatory sequence are tissue-specific mammalian transcriptional regulatory sequences; or (b) said first inducible mammalian transcriptional regulatory sequence and said second inducible mammalian transcriptional regulatory sequence are tumor-suppressor mammalian transcriptional regulatory sequences.</p> |
申请公布号 |
EP2500428(A2) |
申请公布日期 |
2012.09.19 |
申请号 |
EP20110196209 |
申请日期 |
2008.07.10 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD. |
发明人 |
NISSIM, LIOR;BAZ-ZIV, ROY |
分类号 |
C12N15/10;C12N15/85;C12Q1/68;G01N33/50 |
主分类号 |
C12N15/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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