发明名称 |
OVARIAN MARKERS OF OOCYTE COMPETENCY AND USES THEREOF |
摘要 |
<p>The present invention relates to the competence of oocytes to fertilization, uterine implantation and development into a living being. The invention describes ovarian markers whose expression is predicative of oocyte competency that are detected and/or measured in follicular fluid, cumulus cells and/or follicular cells of a mammal. Also described are methods for evaluating competence of mammalian oocytes, methods for selecting a mammalian oocyte for assisted reproduction (AR), and screening methods for identifying stimulatory or inhibitory compounds to mammalian oocyte competence.</p> |
申请公布号 |
EP2499485(A1) |
申请公布日期 |
2012.09.19 |
申请号 |
EP20100829421 |
申请日期 |
2010.11.12 |
申请人 |
UNIVERSITE LAVAL |
发明人 |
SIRARD, MARC-ANDRE;ASSIDI, MOURAD;HAMEL, MELANIE;ROBERT, CLAUDE;KOVAROVA, HANA |
分类号 |
G01N33/48;A61K49/00;C12N15/873;C12Q1/00;C12Q1/68;C40B30/00;G01N33/68 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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