发明名称 |
COMPOSITIONS AND METHODS FOR TREATING OCULAR DISEASES AND CONDITIONS |
摘要 |
The present invention relates to compositions and methods for prevention and treatment of diseases and conditions, particularly ocular diseases and conditions, characterized by aberrant fibrogenesis or scarring, inflammation, and/or aberrant neovascularization or angiogenesis. The compositions and methods of the invention utilize immune-derived moieties that are specifically reactive against the bioactive lipid, sphingosine-1-phosphate, and its variants, which moieties are capable of decreasing the effective concentration of bioactive lipid being targeted. In one embodiment, the immune-derived moiety is a humanized monoclonal antibody that is reactive against sphingosine-1-phosphate. |
申请公布号 |
EP2083862(A4) |
申请公布日期 |
2012.09.19 |
申请号 |
EP20070863554 |
申请日期 |
2007.10.26 |
申请人 |
LPATH, INC. |
发明人 |
SABBADINI, ROGER, A.;GARLAND, WILLIAM, A.;STOLLER, GLENN, L. |
分类号 |
A61K39/395;A61P27/02;C07K16/00;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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