发明名称 |
Anti-system ASC amino acid transporter 2 (ASCT2) antibody |
摘要 |
An object of the present invention is to provide a monoclonal antibody which is useful for treating or diagnosing a disease relating to system ASC amino acid transporter 2 (hereinafter, referred to as“ASCT2”) or a method using the antibody. The present invention provides a monoclonal antibody which specifically recognizes a native three-dimensional structure of an extracellular region of ASCT2 and binds to the extracellular region, or an antibody fragment thereof; a hybridoma which produces the antibody; a DNA which encodes the antibody; a vector which contains the DNA; a transformant obtainable by introducing the vector; a process for producing an antibody or an antibody fragment thereof using the hybridoma or the transformant; and a therapeutic agent using the antibody or the antibody fragment thereof, and a diagnostic agent using the antibody or the antibody fragment thereof.
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申请公布号 |
US8268592(B2) |
申请公布日期 |
2012.09.18 |
申请号 |
US20090505133 |
申请日期 |
2009.07.17 |
申请人 |
SHIRAISHI NORIHIKO;FURUYA AKIKO;TOKI HIROE;ANDO HIROSHI;SUZUKI MASAYO;KUBOTA TSUGUO;KYOWA HAKKO KIRIN CO., LTD |
发明人 |
SHIRAISHI NORIHIKO;FURUYA AKIKO;TOKI HIROE;ANDO HIROSHI;SUZUKI MASAYO;KUBOTA TSUGUO |
分类号 |
C07K16/00;C07K16/28;C12N5/12;C12P21/08 |
主分类号 |
C07K16/00 |
代理机构 |
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主权项 |
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地址 |
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