AZOPHOSPHORUS COMPOUND AND AZOLE COMPOUND LIBRARY AND METHOD FOR PRODUCING SAME

摘要

The purpose of the invention is to provide a method for the efficient production of a sufficiently diverse library that can be used to screen for compounds that will bind with a target substance having protease activity. The invention provides a method for producing an azophosphorus compound library comprising two or more azophosphorus compounds wherein, in the peptide represented by formula (I) A-(Xaa0)-n-B (I) [where m number of Xaa0 represent an arbitrary amino acid, but at least one is an amino acid selected from the group consisting of Cys, Ser, Thr or 2,3-diamino acid, and analogs thereof; m is an integer selected from 2 to 40; and A and B are each independently peptides formed from 0 to 100 amino acids], an azophosphorus skeleton has been introduced to the Cys, Ser, Thr, or 2,3-diamino acid of Xaa0 and at least one analog thereof.