METHOD FOR SCREENING FOR COMPOUND CAPABLE OF ENHANCING OR INHIBITING OATP1B1 TRANSPORT ACTIVITY, AND METHOD FOR DETERMINING EXPRESSION LEVEL OF OATP1B1

摘要

The present invention provides a method for screening for a compound that is capable of enhancing or inhibiting OATP1B1 transport activity, said method using dichlorofluorescein. The present invention also provides use of dichlorofluorescein in determination of the expression level of OATP1B1. The present invention also provides a method for determining the expression level of OATP1B1 in a test cell, said method using dichlorofluorescein. The present invention also provides use of a kit, which comprises dichlorofluorescein and an OATP1B1-expressing positive cell, in determination of the expression level of OATP1B1 in a test cell.