发明名称 AGENTS DERIVED FROM HOLOPTELEA INTEGRIFOLIA AND THEIR COMPOSITIONS FOR THE CONTROL OF METABOLIC SYNDROME AND ASSOCIATED DISEASES
摘要 The invention discloses phytochemical agents derived from Holoptelea integrifolia and novel composition(s) comprising at least one component selected from the extract(s), fraction(s) and active compound(s) for the protection and alleviation of Metabolic Syndrome, insulin resistance, endothelial dysfunction, chronic kidney disease, atherosclerosis, diabetes and other disease conditions associated with metabolic syndrome. The invention also discloses the amelioration of certain biomarker molecules such as Peroxisome proliferator-activated receptor gamma (PPAR-γ), Adipose Differentiation Related Protein (ADRP), CD36, Adipocyte Fatty-acid-Binding Protein (aP2/FABP-4/A-FABP), beta-3 Adrenergic Receptor (β3AR), Leptin, Perilipin and Adiponectin by using the phytochemical components derived from Holoptelea integrifolia.
申请公布号 US2012231095(A1) 申请公布日期 2012.09.13
申请号 US200913510815 申请日期 2009.11.19
申请人 GOKARAJU GANGA RAJU;GOKARAJU RAMA RAJU;GOKARAJU VENKATA KANAKA RANGA RAJU;GOLAKOTI TRIMURTULU;BHUPATHIRAJU KIRAN;CHIRRAVURI VENKATESWARA RAO;CHILLARA SIVARAMAKRISHNA;LAILA NUTRACEUTICALS 发明人 GOKARAJU GANGA RAJU;GOKARAJU RAMA RAJU;GOKARAJU VENKATA KANAKA RANGA RAJU;GOLAKOTI TRIMURTULU;BHUPATHIRAJU KIRAN;CHIRRAVURI VENKATESWARA RAO;CHILLARA SIVARAMAKRISHNA
分类号 A61K31/4458;A61K31/047;A61K31/4425;A61K31/513;A61K31/52;A61K36/16;A61K36/185;A61K36/42;A61K36/482;A61K36/54;A61K36/67;A61K36/81;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P7/00;A61P9/10;A61P9/12;A61P29/00;A61P31/00;G01N30/90 主分类号 A61K31/4458
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