| 发明名称 |
HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS |
| 摘要 |
The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer. |
| 申请公布号 |
US2012232055(A1) |
申请公布日期 |
2012.09.13 |
| 申请号 |
US201113272079 |
申请日期 |
2011.10.12 |
| 申请人 |
MITCHELL IAN S.;BLAKE JAMES F.;XU RUI;KALLAN NICHOLAS C.;XIAO DENGMING;SPENCER KEITH LEE;BENCSIK JOSEF R.;WALLACE ELI M.;SCHLACHTER STEPHEN T.;BANKA ANNA L.;LIANG JUN;SAFINA BRIAN;ZHANG BIRONG;CHABOT CHRISTINE;DO STEVEN;GENENTECH, INC.;ARRAY BIOPHARMA INC. |
发明人 |
MITCHELL IAN S.;BLAKE JAMES F.;XU RUI;KALLAN NICHOLAS C.;XIAO DENGMING;SPENCER KEITH LEE;BENCSIK JOSEF R.;WALLACE ELI M.;SCHLACHTER STEPHEN T.;BANKA ANNA L.;LIANG JUN;SAFINA BRIAN;ZHANG BIRONG;CHABOT CHRISTINE;DO STEVEN |
| 分类号 |
A61K31/517;A61K31/5377;A61K31/541;A61K31/553;A61P9/00;A61P15/02;A61P17/00;A61P25/28;A61P29/00;A61P35/00 |
主分类号 |
A61K31/517 |
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