LABELING PRECURSOR COMPOUND, RADIOACTIVELY LABELING COMPOUND, AND PROCESSES FOR PRODUCING THOSE COMPOUNDS

摘要

Provided is a labeling precursor compound which enables the provision of a PET probe comprising a statin compound. A labeling precursor compound represented by formula (I) or formula (IV). In formulae (I) and (IV), R11 and R12 independently represent H, a C1-4 alkyl group, a C1-3 alkoxy group or the like; R15 represents a C3-6 cycloalkyl group or the like; Y represents a C1-2 alkyl group, -CH=CH-, -CH=CH-CH2- or the like; Z1 represents -Q-CH2-W-CH2-CO2R16 or a group represented by formula (II) or (III); Q represents -C(O)- or -CH(OH)-; W represents -C(O)- or -CH(OH)-; and R16 represents H, an alkyl group or the like. In formula (I), L1 represents -O(CH2)m- or the like; m represents an integer of 1-4; X1 represents a reactive functional group; and R14 represents H, a C1-4 alkyl group or the like. In formula (IV), M represents a boronic acid ester.