COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERURICEMIA

摘要

The present invention is directed to methods and compositions for reduction of uric acid levels in subjects, and methods and compositions that are useful for treating, suppressing and/or preventing afflictions related to elevated uric acid levels in subjects. The methods comprise administering to the subject an effective amount of compound I, or a pharmaceutically acceptable salt or hydrate thereof, or a composition comprising compound I, or a pharmaceutically acceptable salt or hydrate thereof, and a pharmaceutically acceptable carrier. The compositions and/or methods may further comprise administering to the subject an effective amount of xanthine oxidase inhibitor such as allopurinol, or a pharmaceutically acceptable salt or hydrate thereof.