| 发明名称 |
POLYSPECIFIC BINDING MOLECULES AND USES THEREOF |
| 摘要 |
The present invention relates to polyspecific binding molecules and particularly single-chain polyspecific binding molecules that include at least one single-chain T-cell receptor (sc-TCR) covalently linked through a peptide linker sequence to at least one single-chain antibody (sc-Ab). Further disclosed are methods and compositions for testing and using the molecules.
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| 申请公布号 |
US2012230995(A1) |
申请公布日期 |
2012.09.13 |
| 申请号 |
US201113335362 |
申请日期 |
2011.12.22 |
| 申请人 |
WEIDANZ JON A.;CARD KIMBERLYN F.;SHERMAN LINDA A.;KLINMAN NORMAN R.;WONG HING C.;ALTOR BIOSCIENCE CORPORATION |
发明人 |
WEIDANZ JON A.;CARD KIMBERLYN F.;SHERMAN LINDA A.;KLINMAN NORMAN R.;WONG HING C. |
| 分类号 |
A61K39/395;C12N15/09;A61K31/7125;A61K38/00;A61P35/00;A61P43/00;C07H21/04;C07K14/725;C07K16/18;C07K16/22;C07K16/28;C07K19/00;C12P21/02;C12R1/91 |
主分类号 |
A61K39/395 |
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