| 发明名称 |
PYRIDO [2, 3 - B] PYRAZINE DERIVATIVES AND THEIR THERAPEUTICAL USES |
| 摘要 |
<p>The present invention relates to novel pyrido[2,3-b]pyrazine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors.</p> |
| 申请公布号 |
WO2012119690(A1) |
申请公布日期 |
2012.09.13 |
| 申请号 |
WO2012EP00630 |
申请日期 |
2012.02.13 |
| 申请人 |
MERCK PATENT GMBH;DORSCH, DIETER;JONCZYK, ALFRED;HOELZEMANN, GUENTER;AMENDT, CHRISTIANE;ZENKE, FRANK |
发明人 |
DORSCH, DIETER;JONCZYK, ALFRED;HOELZEMANN, GUENTER;AMENDT, CHRISTIANE;ZENKE, FRANK |
| 分类号 |
C07D471/04;A61K31/5025;A61P35/00 |
主分类号 |
C07D471/04 |
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