| 发明名称 |
MULTI-EPITOPIC VACCINE |
| 摘要 |
The present invention relates to isolated polypeptides comprising: (i) a protein transduction domain consisting of ZEBRA or a fragment thereof that retains the capacity of internalization, (ii) at least one CD4+ epitope; and (iii) at least one CD8+ epitope. It also relates to antigen presenting cells loaded with said polypeptides, and the use thereof in immunotherapy including prevention and/or treatment of cancers or infectious diseases.
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| 申请公布号 |
US2012231030(A1) |
申请公布日期 |
2012.09.13 |
| 申请号 |
US201213415877 |
申请日期 |
2012.03.09 |
| 申请人 |
DEROUAZI MADIHA SABIHA;WALKER PAUL R.;DIETRICH PIERRE-YVES;HOPITAUX UNIVERSITAIRES DE GENEVE;UNIVERSITE DE GENEVE |
发明人 |
DEROUAZI MADIHA SABIHA;WALKER PAUL R.;DIETRICH PIERRE-YVES |
| 分类号 |
A61K39/00;A61N5/00;A61P31/00;A61P35/00;A61P37/00;A61P37/04;A61P37/06;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/078;C12N5/0781;C12N5/0784;C12N5/0786;C12N5/10;C12N15/62;C12N15/63;C12P21/02 |
主分类号 |
A61K39/00 |
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