| 发明名称 |
METHODS FOR TREATING CONDITIONS ASSOCIATED WITH C-FMS |
| 摘要 |
Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-1, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages. |
| 申请公布号 |
US2012230987(A1) |
申请公布日期 |
2012.09.13 |
| 申请号 |
US201213466850 |
申请日期 |
2012.05.08 |
| 申请人 |
BRASEL KENNETH ALLAN;SMOTHERS JAMES F.;CERRETTI DOUGLAS PAT;MEHLIN CHRISTOPHER;SUN JILIN;FOSTER STEPHEN;AMGEN INC. |
发明人 |
BRASEL KENNETH ALLAN;SMOTHERS JAMES F.;CERRETTI DOUGLAS PAT;MEHLIN CHRISTOPHER;SUN JILIN;FOSTER STEPHEN |
| 分类号 |
A61K39/395;A61P1/00;A61P3/10;A61P17/00;A61P17/06;A61P19/00;A61P19/02;A61P25/28;A61P29/00;A61P35/00;A61P35/02;A61P37/06 |
主分类号 |
A61K39/395 |
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