| 摘要 |
The invention relates to pyridazinone and pyridone com- pounds having formula (I) or (I'), and pharmaceutically acceptable salts, hydrates, and solvates thereof (I) wherein R1 / R4 and X and X3 are as defined in the claims. The invention further relates to their use as inhibitors of copper-containing amine oxidases. The present invention also relates to the preparation of the aforementioned com- pounds and to pharmaceutical compositions comprising as an active ingredient(s) one or more of the aforementioned compounds, pharmaceutically acceptable salts, hydrates, or solvates thereof. |
| 申请人 |
BIOTIE THERAPIES CORPORATION;PIHLAVISTO, MARJO;SMITH, DAVID;JUHAKOSKI, AUNI;FULOP, FERENC;LAZAR, LASZLO;SZATMARI, ISTVAN;MIKLOS, FERENC;SZAKONYI, ZSOLT;KISS, LORAND;PALKO, MARTA |
发明人 |
PIHLAVISTO, MARJO;SMITH, DAVID;JUHAKOSKI, AUNI;FULOP, FERENC;LAZAR, LASZLO;SZATMARI, ISTVAN;MIKLOS, FERENC;SZAKONYI, ZSOLT;KISS, LORAND;PALKO, MARTA |
